Five days ago, our hamster escaped and this time it was serious. She had escaped before, but usually, she would just be playing outside her enclosure with a spare hamster wheel that I had sitting there. This time was different. I am not sure how long after she actually escaped we found out. She is 12 months old now and has turned a little bit into a sleeper. Sometimes she doesn't leave her little wooden house, and we don't see her for a day or so. As soon as we found out, it was code red in our household. Search and rescue mission on! We checked everywhere: all hidden corners, the pantry, bedrooms, in the beds, toilets, kitchen. We even unloaded the whole storage room. It was a madhouse. This saga continued for several days, and it started to wear on the family: the kids were sad and upset, my wife was grumpy, and I was grumpy. I just could not figure out where she could have gone. We live on the 2nd floor of a flat building, and there is no way she could have left the apartment. It just puzzled me. Then last night, at 11 pm, after we had given up, to be honest, my wife heard a sound coming from the refrigerator. A sound that a refrigerator is not supposed to make. Sometimes the sound was there and then nothing for a while. We heard it a few times, and it started to dawn on us that it vaguely resembled the sound of a hamster trying to get out of a confined space. Our refrigerator is huge and loaded with stuff, but we managed to wrestle it from the wall. We got the toolbox out and started unscrewing the lower panels at the bottom of the refrigerator. And there she was... Thank God. She did not want to come out at first, but some cheese cubes did the trick. She was fine, but she probably got a whack from a spinning fan blade because her tail looked a little crooked. It looks a lot better today. Anyways... the moral of the story... when your hammie escapes, don't give up too soon. They are resilient little animals, and surviving is in their blood!! Enjoy, everybody.

Cordyceps is a parasitic edible fungus, which is a unique Chinese medicinal material. It has been reported to have immunomodulatory effects and use in kidney disease. Especially, Cordyceps has been used in the treatment of lupus nephritis (LN).
Aim of study
Cordyceps proteins (CP) have a favorable bidirectional immunomodulatory functions and may have therapeutic potential for LN. However, the underlying molecular mechanism remains unknown. So this study aimed to examine the activities of CP in LN and possible mechanism.
Materials and methods
So proteomics was performed to detect proteins components of Cordyceps, and analysis it. In addition, MRL/lpr mice were used to study the progression of LN. The MRL/lpr mice were fed either CP (i.g, 0.5, 1.0, 1.5 g/kg/d), prednisolone acetate (PA, i.g, 6 mg/kg/d), or Bailing capsule (BC, i.g, 0.75 g/kg/d) for 8 weeks.
Results
Our results revealed that CP blocked proteinuria production and renal inflammatory infiltratation in MRL/lpr mice to reduce the renal fibrosis. In addition, CP worked better than BC which is artificial Cordyceps fungus powder in regulating proteinuria to urine creatinine ratio and interleukin-4(IL-4) protein amount.
Conclusion
CP could be a potential anti-inflammatory immune product with strong regulatory effects and potency than BC and PA in nephritis therapeutics.
Full:
-https://www.sciencedirect.com/science/article/abs/pii/S0378874123001526

Grifola frondosa is an edible medicinal mushroom that has been proven to have a variety of health benefits. The main active ingredients of this mushroom are polysaccharides.
In this study, ultrasonic-assisted extraction was used to obtain crude Grifola frondosa polysaccharides (GFPs). Then, purified GFP was obtained after purification. In addition, the administration of GFP in oxazolone (OXZ)-induced ulcerative colitis (UC) in mice was found to prevent weight loss. Different doses of GFP (80, 160, and 320 mg/kg body weight) were used, and sulfapyridine (SASP) was used as a positive control (370 mg/kg body weight) for the treatment of OXZ-induced UC.
After treatment, GFP was found to prevent decreases in colon length and the levels of leukocytes, platelets, and neutrophils in UC mice. Moreover, GFP also decreased the expression of pro-inflammatory cytokines [tumor necrosis factor (TNF)-α and interleukin (IL)-1 β], increased IL-10, and reduced colon injury in UC mice.
The results showed that Under these conditions, the predicted polysaccharide yield was 21.72%, and the actual extraction rate was 21.13%. GFP was also found to have a typical absorption peak, and the GFP extracted using the ultrasound-assisted extraction protocol was mainly β-glucan.
These results indicate that ultrasound-assisted extraction of GFP could reduce OXZ-induced intestinal inflammation as a promising candidate for the treatment of UC, with the potential for development as a food supplement to improve intestinal diseases.
Full:
-https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9941675/

For plain men's wedding bands, are there any significant differences between cheaper vs more expensive brands if the material and design are the same? Apart from better branding, what is the benefit of paying more?
For example, the following titanium rings all have similar shapes at 4 drastically different prices. Why would anyone pay for the Thorsten or DY ring?
King Will Basic 3mm 5mm 6mm 7mm 8mm 9mm SilveBlack Titanium Ring Matte Finished Wedding Band Comfort Fit Beveled Edge Amazon.com - ~$16
The Infinity Men's Silver Wedding Ring – Modern Gents (modgents.com) - ~$50
PETERSON Titanium Polished Finish Domed Men’s Wedding Band - 8mm Larson Jewelers (thorstenrings.com) - ~$180
DY Classic Band Ring in Grey Titanium David Yurman - ~$425
If anyone has recommendations on which stores to get a plain classic wedding band from, that would be greatly appreciated!

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All right so i finished the books months ago so some details might be off but here it is. When you think about it for those who never made it to a vessel before they died that must be pretty bad. My theory is that skilled people who aren't tethered together by something like memory stone get kinda ripped apart by the current. In the last book shrewd and chade both seem almost delirious trying to convince fitz to make the horrible choice of joining them. The only one who isn't is Verity who is whole and clear. That must be a kinda horrible fate for people like chade who are kinda caught between tranquility and losing themselves. Obviously, this is all a reach but what do you guys think?
​
edit: i also just remembered. Nighteyes the only one of them to remember what they told him seemed terrified of dying outside of the stone as he believed that would be the end of their existence in there form so that would imply he didn't think chade and shrewd were really themselves as they were before death.

Hi everyone. Just wanted to know if somebody else's cat was doing this and what does it mean? Should I take him to the vet? How do I get him to stop?
Check my last post if you want, to know more about our situation.
In short, we moved a couple of days ago. New house, new rules, I can imagine it's been stressful for him. But it's becoming quite challenging for us too. He wakes us up by digging at his litter box every 5 minutes. He continues to do this whenever we're around, but he doesn't do anything (no pee, or poo). He does position himself as if he's peeing, but I've checked the litter immediately after, and there's nothing. So basically all he's doing is tossing the litter around and carrying it all over the apartment (I know he doesn't do this purposefully, but it's still annoying). He will come out of the litter box and start meowing our ears off. Why is he doing this?
It's a new toilet, and it has a lid. He was using a toilet without the lid prior to this. I've tried removing the lid, but nothing changed, only that he was literally throwing sand around.
I'm considering taking him to the vet because I don't know if it's stress, a UTI or something else. Does anyone know what it means and what can I do to stop it?
P.s. just as I was writing this, he used the litter box 3 times!!!

I am a single mom who has been dating my s.o. for a little over 9 months. We live about two hours apart so we usually only see each other on the weekends. We communicate by text and the occasional phone call in between. My kids are all 12 and up and they are used to having me to themselves. Even when I was married to their dad I was alone more often than not as his work took him all over the country, sometimes for months at a time. All of my kids love to talk to me, which I am incredibly grateful for, and I am in the process of getting my masters degree. I also have an internship at which I am doing work that is very important to me. All that being said, I am an introvert and I place a very high value on what little alone time I get. I have explained this to my s.o. on various occasions but he still seems to think it is romantic to text me after I have told him that I am winding down for the evening and need some time to myself (I try to take about an hour or so each evening before I go to bed, especially on weeknights). I have even gone so far as to mute notifications from him so I can properly wind down.
In addition to this we have discussed multiple times that he can stay over for the weekend but that my kids would prefer him not to be here during the week, not because they don’t like him, but because it impacts their morning routines (they are used to walking through my bedroom to get things from my bathroom in the morning and having a few minutes to talk with me before they leave for school and, understandably, feel uncomfortable to do so when he is here). In spite of having had this discussion he still has to be reminded when it is time to leave. It seems that if I never told him to leave, he would stay indefinitely. His feelings are hurt every time I tell him that it is time for him to go, even when I try to put it as gently as possible (for example, I have tried to establish with him that time to go home is after dinner on Sundays, so I give him dinner and when he is done eating, if he has not indicated that he is getting ready to leave of his own accord, I might ask him if he plans to make any special stops on his way home tonight).
I also feel angry when he tells me “Your kids should be doing this or that.” I have repeatedly told him that we simply have different parenting ideals (he has a teen who does not live with him) and that I do not appreciate when he does that, but he continues to do it. I have been considering cutting ties with him over these issues but sometimes feel like maybe I am being unfair to expect so much. How should I proceed?

What's the best way to handle a difficult boss?

I moved into a new apartment in January and at first chocked the weirdness up to my paranoia. I have been hearing things while I’m in the bathroom and home along. Two times it’s been my boyfriend’s voice clearly speaking to me when he’s not home, and two times it was my dog who has a very distinct whine (I know that sounds so cliche but he’s a cranky old dog and has almost theatrical sound effects). We have some magnetic spice shelves on the fridge, and yesterday I looked over at one right as it began slowly tilting forward off the fridge. All it had on it at the time were two spice jars and some honey, and can withstand much higher weights. I checked to make sure the magnet was secured but when I realized they are I got spooked and busied myself with other things. I went to fill the bathtub up to soak a delicate scarf, but knew the water would take a second to warm up so after I turned the tub on I left the room to get my phone. When I returned the water had been switched to the shower setting rather than the faucet, which takes some strength. I got so freaked out and ran to the living room. I couldn’t move until my boyfriend got home. I started searching things about our town and found a dead files episode about the whole town being haunted (I started the episode but embarked on some adhd fueled mission halfway through, so I’m not sure how that was resolved). Oddly enough the beginning of the episode takes place at a local crystal shop (that I go to!) and goes into how a male spirit will mess with people in the bathroom and also follow people home.

I saw the video in 2016 and can't find it anymore not on YouTube. It was posted on YouTube it's title being in a foreign language probably korean but I'm not sure. The video was 2d animated and resembled 1990s Ghibli animation but was not from any anime, the video had a purple gradient overall. The video was set in a dystopian future portraying a girl in a room of a apartment, surrounded by small animal stuffed toys. Stacked in shelfs lying on the floor and walking around the room specifically two soft toys of a frog and bear. The girl was in a process of making more soft toys sewing it and adding finishing touches in all this she hears footsteps and looks tensed. She then rushes out the room and stats running from the two police officers who came to apprehend the girl. They started chasing her but the girl was fast. In the mist of all this the video keeps showing a train that moving in the crowded town. The girl running made her way to this train. A giant clump of smaller soft toys and clothes making a frog soft toy walking around the streets and causing haveck and heads towards the train. This plot may be wrong but I'm sure of the start. Another thing of this video was it was very slow I had to put it in 2× speed to make it look normal. I do not know when it was uploaded on YouTube but it was probably around 2009 or 2011.

I saw the video in 2016 and can't find it anymore not on YouTube. It was posted on YouTube it's title being in a foreign language probably korean but I'm not sure. The video was 2d animated and resembled 1990s Ghibli animation but was not from any anime, the video had a purple gradient overall. The video was set in a dystopian future portraying a girl in a room of a apartment, surrounded by small animal stuffed toys. Stacked in shelfs lying on the floor and walking around the room specifically two soft toys of a frog and bear. The girl was in a process of making more soft toys sewing it and adding finishing touches in all this she hears footsteps and looks tensed. She then rushes out the room and stats running from the two police officers who came to apprehend the girl. They started chasing her but the girl was fast. In the mist of all this the video keeps showing a train that moving in the crowded town. The girl running made her way to this train. A giant clump of smaller soft toys and clothes making a frog soft toy walking around the streets and causing haveck and heads towards the train. This plot may be wrong but I'm sure of the start. Another thing of this video was it was very slow I had to put it in 2× speed to make it look normal. I do not know when it was uploaded on YouTube but it was probably around 2009 or 2011.

I'm behind in life. 37 yo female- I feel I just was 27 yesterday living my best life- but I'm clinging to that happy time so bad, and I really cant get that back it seems.
​
Ive swapped careers, gave up everything to become a flight attendant after being a teacher, had the time of my life, and now moved back home in an apartment by myself to do nursing school, no SO , no kids, the love of my life is a rescue pup..... my early 20s for 10 years how is it, all these years passed since moving home 6 years ago and im just going further down the drain? I'm 37 and used to be so filled with adventure, exploring, everything- sit home alone now, even terrified to go get a cup of coffee by myself. All I want is to be that care free "girl" I was. I would love to go try some fancy martinis in the city I know how to get to park- like its nothing compared to me moving cross country and just being free. I dont have friends here anymore, I used to thrive on being that free spirit girl who did everything on a whim- now I am turning into an old women whos lost her sense of adventure.
Ive made lists of like places within a 10 mile radius to go try for a dinner, bought tickets to shows... but come time to go- I get so filled with anxiety I stay home.
Ive talked to therapists, but took a break. I wonder if anyone was like this too.

Allora per farla breve ho sempre amato il settore dell'informatica ma il mio diploma non mi permette di lavorarci e quindi mi chiedevo: c'è la possibilità che tramite dei corsi possa trovare spazio in questo settore e fare carriera anche se il mio diploma riguarda tutt'altro? Se sì quali sono questi corsi? Grazie in anticipo a chi risponderà.

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Per sempre insieme: la guida completa per trovare la tua anima gemella, trasformarla nella tua fidanzata e far durare la relazione per sempre Sogni di trovare “quella giusta” con cui condividere la tua vita, ma non sai da dove cominciare? Ti sei già fidanzato ma la monotonia sta spegnendo la scintilla e vorresti una relazione più appagante e felice? “Per sempre insieme” è il percorso formativo ideale per te. Si tratta dell’unico corso in Italia che ti insegna a trovare la tua donna ideale, entrare in una relazione sana e gestirla nel corso degli anni per fare in modo che la scintilla non si spenga mai. Potrai guardare le lezioni pre-registrate online quando vuoi, dal tuo computer o telefono, e avrai anche la possibilità di avere un coaching privato con Luca, il fondatore di Approcciala.it, per avere un supporto personalizzato e indirizzarti sulla strada giusta. Il corso si divide in tre moduli principali. Nel primo modulo, imparerai a trovare “quella giusta” e farla diventare tua fidanzata. Imparerai la mentalità e i requisiti fondamentali per avere una relazione di coppia sana, come capire quale tipo di ragazza ti piace realmente, quali sono le attività da fare con lei per farla diventare la tua fidanzata e come affrontare la conversazione “Cosa siamo?”. Nel secondo modulo, imparerai cosa fare a inizio relazione per partire bene fin da subito ed evitare che la ragazza prenda il controllo. Imparerai come impostare le giuste aspettative per evitare problemi in seguito e come evitare che la relazione ti sfugga di mano e vada nella direzione sbagliata. Nel terzo e ultimo modulo, imparerai come gestire la relazione nel corso degli anni per fare in modo che la scintilla non si spenga mai. Imparerai a evitare che la monotonia spegni la passione, a gestire gli imprevisti e le crisi e a far sì che la vostra relazione duri per sempre. “Per sempre insieme” è per chi cerca una relazione seria e duratura. Se sei single e vuoi trovare “quella giusta” con cui condividere la tua vita, o se hai già una relazione in corso ma vuoi renderla più appagante e felice, questo corso è per te.
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The courage to be done and leave has nothing to do with proving anything to him. It’s no longer about him. He blew it. He disappointed you and betrayed your feelings. It’s all about not disappointing yourself now. The most loving thing I did for myself to earn my own trust back is ACCEPT the package he delivered at the footsteps of my door which is the parts of myself I am ashamed of. It’s not the things he accused me of, my friend put it this way, “Any criticism someone sends that is black and white is not valid because it’s not balanced, it’s just their venom. It’s not you.” Shadow work is acknowledging and not running from your feelings during dark times, heal yourself.
Gaslighting makes you guarded, shut down and numb. You have to grab onto friends who you identify as sweet and literally let yourself fall apart and ASK FOR HELP. I struggle with that one. You need people to get through the pain, (otherwise addiction born from isolation becomes a problem).
In the pieces you are going to rebuild something stronger. Things need to completely break down to allow for a stronger and better system.
* Like the Chicago fire, everything was built of wood and a small fire ripped through the whole city. What stood was the water tower, think of that as yourself. You have to see that you will survive, any man who swears and undying love for you at the price of your freedom doesn’t actually love you, he just feels masculine when women soften around him and he’s the fire that burned your softness. He threw down in attempt to bend your will and was strong enough to get you. But now you see wood doesn’t work and that that’s what fire does. So build yourself out of stone and brick and metal. He can try to burn you but all it will do is heat you enough to burn him back the next time he tries to manipulate you by presenting his softness. You are showing him his own medicine because he no longer has access to you. And that, is freedom from abuse.

I just found out my wife is trying to see other women
Me (23m) and my wife (23f) have known each other since we where two years old. We didn’t start dating until 2020 and got married 2022. We just moved across the state together and I thought everything was going good until the other day. I couldn’t sleep and woke up to her using a dating site to find girls in our area. She doesn’t know I woke up and saw this while laying next to her in bed. Originally I just believed she was trying to make new friends and meet new people so I didn’t say anything. Something just wasn’t sitting right so while she was asleep last night I went through her phone (something she’s done regularly to me but I’ve never done to her). And she’s actually been trying to hookup and flirt with these other women while I’m at work. She’s also convinced me to let her friend couch surf here starting next week for a month while waiting in her new apartment to let her move in. Which I only agreed to before knowing she was trying to (or possibly has) cheat on me with women. I haven’t confronted her and don’t know if I should or how to go about it, any advice here would help.